Best approach- to do profiling for large dataset (20 million records)

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Hello ,

I need to do profiling for tables which have more than 20million records and also the table will get update with new records as every week.

1) Is that right to do profiling for such a large dataset, will i get any performance issue?
2) as the table gets updated with new record as weekly basis, is that possible that i can refresh my dataset in experian by only adding new records (incremental load)

Kindly suggest some best apporach to do profiling for tables like this.

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